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IISER Mohali HRMS Central Facility

Waters Synapt G2-Si Q ToF Mass Spectrometer
Key Features

Highly complex samples screening require:

Chromatographic Resolution: UPLC/nano LC
High resolution MS & MSMS spectra:> 50,000
Fast acquisition rate: 30 spect/sec
High in spectrum dynamic range: 30 spect/sec
Quantitative response: > 5 orders
Excellent exact mass performance: > 5 orders
Excellent exact mass fragment ions: < 1ppm
Correct isotope ratios: < 1ppm
Isobaric & Chimeric Separations: Ion Mobility
High sensitivity: MS & MSMS
Characterize trace levels in complex matrix: Xevo Source
Comprehensively catalog complex samples
Simple setup and use: Dynamic R

All at the same time: : MSE
HRMS machine

Features:

MS; MS-MS; alternative MALDI & ESI ionization; separate modes for high accuracy, high resolution, high sensitivity; Ion Mobility MS, Atmospheric Solid Sample Probing

HRMS machine

HRMS machine

Applications:

Small molecule characterization: Exact mass determination, chemical structure determination, identification and quantitation of small molecules in either homogenous (largely-pure, synthetic) or heterogenous (biological tissue-derived) samples.

Biomacromolecular characterization and 'omics': Intact mass determination of macromolecules, peptide/protein characterization through mass fingerprinting and amino acid sequencing, protein post-translational modification detection and characterization (including glycan analysis), highthroughput LC-coupled protein identification in serum or tissue-derived samples, quantitation of protein/peptide amounts in any kind of sample.

Sample submission procedure for samples of other Academic Universities/Institutes & Industries:

The details regarding the charges and sample submission procedure will be announced here soon.

Sector-81 S.A.S. Nagar Mohali, Manauli PO 140306
Punjab India
Telefax: +91-0172-2240266
Email: sababu@iisermohali.ac.in


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